"Is this something you want? It is related to the recent discussions on disease-activity free status in trying to predict who responds to treatment or not! This is a discussion that should be happening. You should ask your neurologists to set a target and aim for that; i.e. treat-to-target or TOT. This is a concept the rheumatologists use that we should adopt. TOT was discussed at the Cleveland meeting and there was a general consensus that we should adopt the concept in MS."